immunoMUSE®
Multiplex without limits. Detect more, faster, and with unmatched sensitivity.
Choose your antibodies and build your own panel with immunoMUSE® Activate & Amplify kits
• ideal for FFPE sections
• 1-plex, 2-plex and 4-plex kits
• fluorophores 488nm, 565 nm, 647nm, 750 nm
High-sensitivity immunofluorescence with no species or isotype constraints – all in one seamless workflow.
immunoMUSE® kits are designed for researchers who need more from multiplex staining: more flexibility, more sensitivity, and more confidence in challenging samples.
Use your existing validated primary antibodies (BSA and azide free), detect low abundance targets with higher sensitivity than secondary antibodies, and generate results the same day in a workflow that fits easily into your lab.
Multiplexing should not limit your biology
Traditional multiplex workflows force compromises. Researchers working with FFPE tissue, low-abundance biomarkers, and complex immune environments often have to choose between sensitivity, workflow complexity, and panel flexibility. In many cases, repeated staining cycles can also risk morphological damage.
immunoMUSE®
is built to remove those compromises
With an all-in-one solution for high-sensitivity multiplexing, immunoMUSE® helps you:
• detect weak and low-expression targets
• preserve spatial context and morphology
• avoid species and isotype restrictions
• simplify multiplex workflows
• integrate multiplex staining into existing lab processes
The all-in-one solution for high-sensitivity multiplexing
Multiplex without constraints
Combine antibodies freely without species or isotype limitations. Design your panel around biology, not around secondary antibody compatibility.
Higher sensitivity than secondary antibodies
Detect low-abundance biomarkers with strong, clear signal. immunoMUSE® is designed for challenging targets and difficult samples where conventional secondary antibody workflows often fall short.
Compatible with your existing primary antibodies
Keep using the validated antibodies (BSA and azide free) you already trust.
Seamless workflow integration
immunoMUSE® fits into your existing immunofluorescence workflow, helping reduce complexity while improving consistency and turnaround time.
Automated
Built for scalable lab operations and ready for automation-friendly workflows, supporting reproducibility across batches and users.
Same-day results
Move from staining to imaging in one day, so your team can generate answers faster without adding workflow burden.
Built for real-world research challenges
Oncology and tumor microenvironment research
Cancer biology labs, tumor immunology groups, and pathology or translational oncology teams often work with FFPE tissue, weak low-abundance biomarkers, limited samples and heterogeneous tumors. They need the flexibility to test custom tumor and immune marker combinations without sacrificing sensitivity or tissue quality. immunoMUSE® supports multiplex staining of up to 4 markers, signal amplification without loss of spatial resolution, and flexible use of validated antibodies.
Immunology and infectious disease research
Vaccine and infection research labs, transplant pathology teams, and autoimmune disease groups frequently face limited samples, complex immune subsets, low cytokine expression, and high background. immunoMUSE® helps deliver high signal-to-noise detection and multiplex capability for immune profiling in difficult tissues.
Neuroscience and neuroimmunology
Neuropathology and neurodegeneration labs often work with heterogeneous tissue, facing strong autofluorescence, complex backgrounds, and low protein abundance. Neuroimmunology groups need to resolve low abundance inflammatory markers in dense tissue environments. immunoMUSE® is designed to improve signal detection in exactly these conditions while preserving spatial detail.
Upgrade your primary antibodies with the MUSE® technology
Conjugate your primary antibody to the MUSE® activator with immunoMUSE® Activate & Amplify kit
In an easy 2 days protocol, with low hands-on time, conjugate your primary antibodies of choice to the MUSE® activators provided in the kits.
From sample to result in one day
1. Add your MUSE®-tagged primary antibodies
Use your preferred validated antibodies (BSA- and azide-free) with no species or isotype restrictions.
2. Apply immunoMUSE® Amplifiers
Add immunoMUSE® Amplifiers with the practical droppers provided in the kit.
3. Image your multiplex panel
Generate high-quality multiplex data with preserved morphology and spatial resolution.
No secondary antibody matching. No iterative staining cycles. No unnecessary workflow complexity.
Choose your multiplex solution
New to
immunoMUSE®?
>
Start with immunoMUSE®
Activate & Amplify kits
Running single- marker assays?
>
Choose 1-plex
Need true
multiplexing?
>
Choose 2-plex
or 4-plex
Scaling
experiments?
>
Use immunoMUSE®
Amplify kits
immunoMUSE® Activate & Amplify Kits
Conjugate your primary antibody to the MUSE® activator and stain.
immunoMUSE® Activate
& Amplify Small
- Conjugation kit
- 5 reactions
- 1-plex format
- Available in 4 fluorophores (488nm, 565 nm, 647nm or 750 nm)
Best for:
Initial testing and proof-of-concept experiments
immunoMUSE® Activate
& Amplify Medium
- Conjugation kit
- 25 reactions
- 1-plex format (available in 4 fluorophores: 488nm, 565 nm, 647nm or 750 nm)
- 2-plex format (488 nm and 647 nm)
- 4-plex format (488nm, 565 nm, 647nm, 750 nm)
Best for:
Method development and assay optimization
immunoMUSE® Activate
& Amplify Large
- Conjugation kit/s
- 50 reactions
- 1-plex format (available in 4 fluorophores: 488nm, 565 nm, 647nm or 750 nm)
- 2-plex format (488 nm and 647 nm)
- 4-plex format (488nm, 565 nm, 647nm, 750 nm)
Best for:
Method development and assay optimization
The 1-plex immunoMUSE® Activate & Amplify kits are designed for single-target detection only and can only be combined for multiplexing following an alternative protocol.
immunoMUSE® Amplify Kits
immunoMUSE® Amplify
Medium
- 25 reactions
- 1-plex format (available in 4 fluorophores: 488nm, 565 nm, 647nm or 750 nm)
- 2-plex format (488 nm and 647 nm)
- 4-plex format (488nm, 565 nm, 647nm, 750 nm)
Best for:
Ongoing experiments and higher throughput
immunoMUSE® Amplify
Large
- 50 reactions
- 1-plex format (available in 4 fluorophores: 488nm, 565 nm, 647nm or 750 nm)
- 2-plex format (488 nm and 647 nm)
- 4-plex format (488nm, 565 nm, 647nm, 750 nm)
Best for:
Ongoing experiments and higher throughput
Stop redesigning your panels. Start discovering more
Multiplexing should help you answer biological questions faster, not force you into technical compromises. immunoMUSE® gives you the freedom to combine antibodies without species or isotype constraints, the sensitivity to detect low-abundance markers, and the workflow simplicity to get results the same day.
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